diff --git a/Configure.pl b/Configure.pl
index 72a5dad..f829d5c 100755
--- a/Configure.pl
+++ b/Configure.pl
@@ -32,7 +32,7 @@ GetOptions(\%args, qw(
     os=s shell=s toolchain=s compiler=s
     ar=s cc=s ld=s make=s has-sha has-libuv
     static has-libtommath has-libatomic_ops
-    has-dyncall has-libffi
+    has-dyncall has-libffi pkgconfig=s
     build=s host=s big-endian jit! enable-jit lua=s has-dynasm
     prefix=s bindir=s libdir=s mastdir=s make-install asan ubsan),
     'no-optimize|nooptimize' => sub { $args{optimize} = 0 },
@@ -99,6 +99,7 @@ $config{config} = join ' ', map { / / ? "\"$_\"" : $_ } @args;
 $config{osname} = $^O;
 $config{osvers} = $Config{osvers};
 $config{lua} = $args{lua} // './3rdparty/dynasm/minilua@exe@';
+$config{pkgconfig} = $args{pkgconfig} // '/usr/bin/pkg-config';
 
 # set options that take priority over all others
 my @keys = qw( ar cc ld make );
@@ -164,12 +165,33 @@ if (-e '3rdparty/libuv/src/unix/threadpool' . $defaults{obj}
     system($defaults{make}, 'realclean')
 }
 
+# test whether pkg-config works
+if (-e "$config{pkgconfig}") {
+    print("\nTesting pkgconfig ... ");
+    system("$config{pkgconfig}", "--version");
+    if ( $? == 0 ) {
+        $config{pkgconfig_works} = 1;
+    } else {
+        $config{pkgconfig_works} = 0;
+    }
+}
+
 # conditionally set include dirs and install rules
 $config{cincludes} //= '';
 $config{install}   //= '';
 if ($args{'has-libuv'}) {
     $defaults{-thirdparty}->{uv} = undef;
     unshift @{$config{usrlibs}}, 'uv';
+    if ($config{pkgconfig_works}) {
+        my $result = `$config{pkgconfig} --cflags libuv`;
+        if ( $? == 0 ) {
+            $result =~ s/\n/ /g;
+            $config{cincludes} .= ' ' . "$result";
+            print("Adding extra include for libuv: $result\n");
+        } else {
+            print("Error occured when running $config{pkgconfig} --cflags libuv.\n");
+        }
+    }
 }
 else {
     $config{cincludes} .= ' ' . $defaults{ccinc} . '3rdparty/libuv/include'
@@ -181,6 +203,16 @@ else {
 if ($args{'has-libatomic_ops'}) {
     $defaults{-thirdparty}->{lao} = undef;
     unshift @{$config{usrlibs}}, 'atomic_ops';
+    if ($config{pkgconfig_works}) {
+        my $result = `$config{pkgconfig} --cflags atomic_ops`;
+        if ( $? == 0 ) {
+            $result =~ s/\n/ /g;
+            $config{cincludes} .= ' ' . "$result";
+            print("Adding extra include for atomic_ops: $result\n");
+        } else {
+            print("Error occured when running $config{pkgconfig} --cflags atomic_ops.\n");
+        }
+    }
 }
 else {
     $config{cincludes} .= ' ' . $defaults{ccinc} . '3rdparty/libatomic_ops/src';
@@ -216,7 +248,8 @@ if ($args{'has-libtommath'}) {
 }
 else {
     $config{cincludes} .= ' ' . $defaults{ccinc} . '3rdparty/libtommath';
-    $config{install}   .= "\t\$(CP) 3rdparty/libtommath/*.h \$(DESTDIR)\$(PREFIX)/include/libtommath\n";
+    $config{install}   .= "\t\$(MKPATH) \$(DESTDIR)\$(PREFIX)/include/libtommath\n"
+                        . "\t\$(CP) 3rdparty/libtommath/*.h \$(DESTDIR)\$(PREFIX)/include/libtommath\n";
 }
 
 if ($args{'has-dynasm'}) {
@@ -232,6 +265,16 @@ if ($args{'has-libffi'}) {
     $config{nativecall_backend} = 'libffi';
     unshift @{$config{usrlibs}}, 'ffi';
     push @{$config{defs}}, 'HAVE_LIBFFI';
+    if ($config{pkgconfig_works}) {
+        my $result = `$config{pkgconfig} --cflags libffi`;
+        if ( $? == 0 ) {
+            $result =~ s/\n/ /g;
+            $config{cincludes} .= ' ' . "$result";
+            print("Adding extra include for libffi: $result\n");
+        } else {
+            print("Error occured when running $config{pkgconfig} --cflags libffi.\n");
+        }
+    }
 }
 elsif ($args{'has-dyncall'}) {
     unshift @{$config{usrlibs}}, 'dyncall_s', 'dyncallback_s', 'dynload_s';
@@ -364,6 +407,7 @@ my $order = $config{be} ? 'big endian' : 'little endian';
 print "\n", <<TERM, "\n";
         make: $config{make}
      compile: $config{cc} $config{cflags}
+    includes: $config{cincludes}
         link: $config{ld} $config{ldflags}
         libs: $config{ldlibs}
 
@@ -873,6 +917,10 @@ Build and install MoarVM in addition to configuring it.
 
 =item --has-libffi
 
+=item --pkgconfig=/path/to/pkgconfig/executable
+
+Provide path to the pkgconfig executable. Default: /usr/bin/pkg-config
+
 =item --no-jit
 
 Disable JIT compiler, which is enabled by default to JIT-compile hot frames.
diff --git a/build/Makefile.in b/build/Makefile.in
index 56a4c8a..b94e847 100644
--- a/build/Makefile.in
+++ b/build/Makefile.in
@@ -454,9 +454,6 @@ install: all
 	$(CP) src/strings/*.h $(DESTDIR)$(PREFIX)/include/moar/strings
 	$(CP) src/jit/*.h $(DESTDIR)$(PREFIX)/include/moar/jit
 	$(CP) src/instrument/*.h $(DESTDIR)$(PREFIX)/include/moar/instrument
-	$(MKPATH) $(DESTDIR)$(PREFIX)/include/libuv
-	$(MKPATH) $(DESTDIR)$(PREFIX)/include/libtommath
-	$(CP) 3rdparty/libuv/include/*.h $(DESTDIR)$(PREFIX)/include/libuv
 @install@
 
 lib: @moar@
diff --git a/build/setup.pm b/build/setup.pm
index 324cc88..c87d79e 100755
--- a/build/setup.pm
+++ b/build/setup.pm
@@ -125,7 +125,7 @@ our %TC_POSIX = (
     ccshared   => '-fPIC',
     ldshared   => '-shared @ccshared@',
     moarshared => '',
-    ldrpath    => '-Wl,-rpath,@libdir@ -Wl,-rpath,@prefix@/share/perl6/site/lib',
+    ldrpath    => '-Wl,-rpath,/@libdir@ -Wl,-rpath,@prefix@/share/perl6/site/lib',
 
     arflags => 'rcs',
     arout   => '',