diff --git a/profiles/default/package.use/exactly-one-of b/profiles/default/package.use/exactly-one-of
index fe6c50583..b28c2b768 100644
--- a/profiles/default/package.use/exactly-one-of
+++ b/profiles/default/package.use/exactly-one-of
@@ -39,6 +39,3 @@ net-analyzer/ossec-hids hybrid postgres
 
 # exactly-one-of ( iptables nftables )
 net-misc/connman -nftables
-
-# exactly-one-of ( python_single_target_python2_7 python_single_target_python3_6 )
-app-arch/rpm -python_single_target_python2_7
diff --git a/profiles/default/package.use/required-by b/profiles/default/package.use/required-by
index 9a38d983a..7a9c703d1 100644
--- a/profiles/default/package.use/required-by
+++ b/profiles/default/package.use/required-by
@@ -389,9 +389,6 @@ dev-libs/protobuf python
 # required by dev-python/tlslite-0.4.3-r1
 dev-libs/cryptlib python
 
-# required by dev-util/osc-0.152.0
-app-arch/rpm python -python_single_target_python3_6 python_single_target_python2_7
-
 # required by dev-util/dput-ng-1.10
 dev-util/distro-info python
 
@@ -686,8 +683,5 @@ net-analyzer/rrdtool graph
 # required by dev-db/myodbc-8.0.19
 dev-db/mysql-connector-c static-libs
 
-# required by dev-util/rpmdevtools-8.10-r2
-app-arch/rpm python_single_target_python3_6
-
 # required by net-firewall/firewalld-0.7.1-r2
 net-firewall/nftables xtables